Original Research

Published on 08 Mar 2022

“CityQuest,” A Custom-Designed Serious Game, Enhances Spatial Memory Performance in Older Adults

in Neurocognitive Aging and Behavior

Niamh A. Merriman
Eugenie Roudaia
Jan Ondřej
Matteo Romagnoli
Ivan Orvieto
Carol O’Sullivan
Fiona N. Newell

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.806418

2,690 views
3 citations

Original Research

Published on 08 Mar 2022

Higher Burden of Cerebral Small Vascular Disease Predicts Major Adverse Cardiac and Cerebrovascular Events and Is Related to Abnormal Blood Pressure Variability Pattern in Hypertension Patients

in Neurocognitive Aging and Behavior

Xiaomeng Xu
Shu Huang
YuE Zeng
Yulan Feng
Dongqi Yue
Fanxia Shen
Yang Gao
Bei Zhang
Yang Yang
Lin Gu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.824705

1,700 views

Original Research

Published on 08 Mar 2022

Different Complement Activation Pathways Underly Cognitive Impairment and Type 2 Diabetes Mellitus Combined With Cognitive Impairment

in Neurocognitive Aging and Behavior

Zhenxing Li
Weiwei Zhang
Feng Gao
Qiqiang Tang
Dongmei Kang
Yong Shen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.810335

2,516 views
2 citations

Original Research

Published on 07 Mar 2022

Concurrent Training Increases Serum Brain-Derived Neurotrophic Factor in Older Adults Regardless of the Exercise Frequency

in Neurocognitive Aging and Behavior

Ermilo Canton-Martínez
Iván Rentería
Patricia C. García-Suárez
José Moncada-Jiménez
Juan Pablo Machado-Parra
Fabio Santos Lira
David K. Johnson
Alberto Jiménez-Maldonado

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.791698

3,859 views
4 citations

Original Research

Published on 07 Mar 2022

Body Mass Index, Waist Circumference, and Cognitive Decline Among Chinese Older Adults: A Nationwide Retrospective Cohort Study

in Neurocognitive Aging and Behavior

Fang Liang
Jialin Fu
Justin B. Moore
Xinge Zhang
Yijia Xu
Nan Qiu
Yechuang Wang
Rui Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.737532

5,410 views
8 citations

Original Research

Published on 04 Mar 2022

Derivation and Validation of the Cognitive Impairment Prediction Model in Older Adults: A National Cohort Study

in Neurocognitive Aging and Behavior

Mingyue Hu
Yinyan Gao
Timothy C. Y. Kwok
Zhanfang Shao
Lily Dongxia Xiao
Hui Feng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.755005

3,879 views
4 citations

Original Research

Published on 04 Mar 2022

Causal Relationships Between Osteoarthritis and Senile Central Nerve System Dysfunction: A Bidirectional Two-Sample Mendelian Randomization Study

in Parkinson’s Disease and Aging-related Movement Disorders

Yuanqing Cai
Guangyang Zhang
Jialin Liang
Zhaopu Jing
Rupeng Zhang
Leifeng Lv
Xiaoqian Dang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.793023

6,956 views
13 citations

Original Research

Published on 04 Mar 2022

Unified Deep Learning-Based Mouse Brain MR Segmentation: Template-Based Individual Brain Positron Emission Tomography Volumes-of-Interest Generation Without Spatial Normalization in Mouse Alzheimer Model

in Alzheimer's Disease and Related Dementias

Seung Yeon Seo
Soo-Jong Kim
Jungsu S. Oh
Jinwha Chung
Seog-Young Kim
Seung Jun Oh
Segyeong Joo
Jae Seung Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.807903

3,211 views
5 citations

Original Research

Published on 04 Mar 2022

Inhibition of Adult Hippocampal Neurogenesis Plays a Role in Sevoflurane-Induced Cognitive Impairment in Aged Mice Through Brain-Derived Neurotrophic Factor/Tyrosine Receptor Kinase B and Neurotrophin-3/Tropomyosin Receptor Kinase C Pathways

in Cellular and Molecular Mechanisms of Brain-aging

Lichi Xu
Yanjing Guo
Gongming Wang
Guoqing Sun
Wei Sun
Jingjing Li
Xinlei Li
Jiangnan Wu
Mengyuan Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.782932

2,861 views
7 citations

Original Research

Published on 03 Mar 2022

Multimodal Magnetic Resonance Imaging Reveals Aberrant Brain Age Trajectory During Youth in Schizophrenia Patients

in Neurocognitive Aging and Behavior

Jiayuan Huang
Pengfei Ke
Xiaoyi Chen
Shijia Li
Jing Zhou
Dongsheng Xiong
Yuanyuan Huang
Hehua Li
Yuping Ning
Xujun Duan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.823502

3,759 views
8 citations

Original Research

Published on 03 Mar 2022

The Association of Pre-existing Diagnoses of Alzheimer’s Disease and Parkinson’s Disease and Coronavirus Disease 2019 Infection, Severity and Mortality: Results From the Korean National Health Insurance Database

in Neuroinflammation and Neuropathy

Ji Hee Kim
In Bok Chang
Yoo Hwan Kim
Chan Yang Min
Dae Myoung Yoo
Hyo Geun Choi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.821235

3,537 views
7 citations

Opinion

Published on 03 Mar 2022

COVID-19 and Aging-Related Genome (Chromosome) Instability in the Brain: Another Possible Time-Bomb of SARS-CoV-2 Infection

in Neuroinflammation and Neuropathy

Ivan Y. Iourov
Svetlana G. Vorsanova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.786264

2,162 views
3 citations

Original Research

Published on 03 Mar 2022

Neurons Release Injured Mitochondria as “Help-Me” Signaling After Ischemic Stroke

in Cellular and Molecular Mechanisms of Brain-aging

Li Gao
Fan Liu
Pin-Pin Hou
Anatol Manaenko
Zhi-Peng Xiao
Fei Wang
Tian-Le Xu
Qin Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.785761

6,978 views
12 citations

Review

Published on 03 Mar 2022

Monogenetic Forms of Parkinson’s Disease – Bridging the Gap Between Genetics and Biomarkers

in Parkinson’s Disease and Aging-related Movement Disorders

Lars Tönges
Eun Hae Kwon
Stephan Klebe

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.822949

3,599 views
2 citations

Original Research

Published on 03 Mar 2022

Low Subicular Volume as an Indicator of Dementia-Risk Susceptibility in Old Age

in Alzheimer's Disease and Related Dementias

Sonja M. Kagerer
Clemens Schroeder
Jiri M. G. van Bergen
Simon J. Schreiner
Rafael Meyer
Stefanie C. Steininger
Laetitia Vionnet
Anton F. Gietl
Valerie Treyer
Alfred Buck

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.811146

2,378 views
4 citations

Original Research

Published on 03 Mar 2022

Machine Learning for Detecting Parkinson’s Disease by Resting-State Functional Magnetic Resonance Imaging: A Multicenter Radiomics Analysis

in Parkinson’s Disease and Aging-related Movement Disorders

Dafa Shi
Haoran Zhang
Guangsong Wang
Siyuan Wang
Xiang Yao
Yanfei Li
Qiu Guo
Shuang Zheng
Ke Ren

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.806828

4,552 views
16 citations

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Articles

“CityQuest,” A Custom-Designed Serious Game, Enhances Spatial Memory Performance in Older Adults

Higher Burden of Cerebral Small Vascular Disease Predicts Major Adverse Cardiac and Cerebrovascular Events and Is Related to Abnormal Blood Pressure Variability Pattern in Hypertension Patients

Different Complement Activation Pathways Underly Cognitive Impairment and Type 2 Diabetes Mellitus Combined With Cognitive Impairment

Concurrent Training Increases Serum Brain-Derived Neurotrophic Factor in Older Adults Regardless of the Exercise Frequency

Body Mass Index, Waist Circumference, and Cognitive Decline Among Chinese Older Adults: A Nationwide Retrospective Cohort Study

Derivation and Validation of the Cognitive Impairment Prediction Model in Older Adults: A National Cohort Study

Causal Relationships Between Osteoarthritis and Senile Central Nerve System Dysfunction: A Bidirectional Two-Sample Mendelian Randomization Study

Unified Deep Learning-Based Mouse Brain MR Segmentation: Template-Based Individual Brain Positron Emission Tomography Volumes-of-Interest Generation Without Spatial Normalization in Mouse Alzheimer Model

Inhibition of Adult Hippocampal Neurogenesis Plays a Role in Sevoflurane-Induced Cognitive Impairment in Aged Mice Through Brain-Derived Neurotrophic Factor/Tyrosine Receptor Kinase B and Neurotrophin-3/Tropomyosin Receptor Kinase C Pathways

Multimodal Magnetic Resonance Imaging Reveals Aberrant Brain Age Trajectory During Youth in Schizophrenia Patients

The Association of Pre-existing Diagnoses of Alzheimer’s Disease and Parkinson’s Disease and Coronavirus Disease 2019 Infection, Severity and Mortality: Results From the Korean National Health Insurance Database

COVID-19 and Aging-Related Genome (Chromosome) Instability in the Brain: Another Possible Time-Bomb of SARS-CoV-2 Infection

Neurons Release Injured Mitochondria as “Help-Me” Signaling After Ischemic Stroke

Monogenetic Forms of Parkinson’s Disease – Bridging the Gap Between Genetics and Biomarkers

Low Subicular Volume as an Indicator of Dementia-Risk Susceptibility in Old Age

Machine Learning for Detecting Parkinson’s Disease by Resting-State Functional Magnetic Resonance Imaging: A Multicenter Radiomics Analysis