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Original Research

Published on 29 Nov 2018

A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Terminal Domain of the Staphylococcus aureus SSL7 Protein

in Molecular Innate Immunity

  • Laure Yatime
  • Nicolas S. Merle
  • Annette G. Hansen
  • Niels Anton Friis
  • Jakob A. Østergaard
  • Mette Bjerre
  • Lubka T. Roumenina
  • Steffen Thiel
  • Peter Kristensen
  • Gregers R. Andersen
A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Terminal Domain of the Staphylococcus aureus SSL7 Protein
Frontiers in Immunology
doi 10.3389/fimmu.2018.02822
  • 4,132 views
  • 7 citations