Original Research

Published on 29 Jul 2020

Redox Imbalance and Oxidative DNA Damage During Isoniazid Treatment of HIV-Associated Tuberculosis: A Clinical and Translational Pharmacokinetic Study

in Translational Pharmacology

Isaac Zentner
Hyun-moon Back
Leonid Kagan
Selvakumar Subbian
Jyothi Nagajyothi
Shashikant Srivastava
Jotam Pasipanodya
Tawanda Gumbo
Gregory P. Bisson
Christopher Vinnard

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01103

3,462 views
1 citation

Opinion

Published on 29 Jul 2020

Rationale for Considering Oral Idasanutlin as a Therapeutic Option for COVID-19 Patients

in Translational Pharmacology

Giorgio Zauli
Veronica Tisato
Paola Secchiero

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01156

2,768 views
17 citations

Review

Published on 24 Jul 2020

From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery

in Translational Pharmacology

Karla de Castro Figueiredo Bordon
Camila Takeno Cologna
Elisa Corrêa Fornari-Baldo
Ernesto Lopes Pinheiro-Júnior
Felipe Augusto Cerni
Fernanda Gobbi Amorim
Fernando Antonio Pino Anjolette
Francielle Almeida Cordeiro
Gisele Adriano Wiezel
Iara Aimê Cardoso

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01132

70,251 views
137 citations

Original Research

Published on 15 Jul 2020

Improving the Therapeutic Effect of Ultrasound Combined With Microbubbles on Muscular Tumor Xenografts With Appropriate Acoustic Pressure

in Translational Pharmacology

Yan He
Meiling Yu
Jie Wang
Fen Xi
Jiali Zhong
Yuwen Yang
Hai Jin
Jianhua Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01057

1,682 views
3 citations

Review

Published on 08 Jul 2020

Advance in Drug Delivery for Ageing Skeletal Muscle

in Translational Pharmacology

Yi Li
Ming Chen
Yanpeng Zhao
Ming Li
Yong Qin
Shi Cheng
Yanyu Yang
Pengbin Yin
Licheng Zhang
Peifu Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01016

8,531 views
8 citations

Review

Published on 03 Jul 2020

Application of Pharmacokinetic-Pharmacodynamic Modeling in Drug Delivery: Development and Challenges

in Translational Pharmacology

Huixi Zou
Parikshit Banerjee
Sharon Shui Yee Leung
Xiaoyu Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00997

60,853 views
45 citations

Mini Review

Published on 02 Jul 2020

Pharmacogenetic Testing for Prevention of Severe Cutaneous Adverse Drug Reactions

in Translational Pharmacology

Chih-Jung Chang
Chun-Bing Chen
Shuen-Iu Hung
Chao Ji
Wen-Hung Chung

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00969

8,901 views
35 citations

Perspective

Published on 30 Jun 2020

Accelerating Therapeutics for Opportunities in Medicine: A Paradigm Shift in Drug Discovery

in Translational Pharmacology

Izumi V. Hinkson
Benjamin Madej
Eric A. Stahlberg

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00770

12,149 views
45 citations

Original Research

Published on 26 Jun 2020

Drug Repositioning for Noonan and LEOPARD Syndromes by Integrating Transcriptomics With a Structure-Based Approach

in Translational Pharmacology

Liyuan Zhu
Ruth Roberts
Ruili Huang
Jinghua Zhao
Menghang Xia
Brian Delavan
Mike Mikailov
Weida Tong
Zhichao Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00927

4,466 views
8 citations

Editorial

Published on 26 Jun 2020

Editorial: Bubbles, Droplets and Micelles for Acoustically-Mediated Drug/Gene Delivery

in Translational Pharmacology

Jean-Michel Escoffre
Baudouin Denis de Senneville
Noboru Sasaki
Marc Derieppe

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00954

1,862 views
1 citation

Original Research

Published on 24 Jun 2020

Inhibition of Plasminogen Activator Inhibitor-1 Activation Suppresses High Fat Diet-Induced Weight Gain via Alleviation of Hypothalamic Leptin Resistance

in Translational Pharmacology

Shinichiro Hosaka
Tetsuya Yamada
Kei Takahashi
Takashi Dan
Keizo Kaneko
Shinjiro Kodama
Yoichiro Asai
Yuichiro Munakata
Akira Endo
Hiroto Sugawara

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00943

5,591 views
9 citations

Original Research

Published on 18 Jun 2020

Dietary Potassium Downregulates Angiotensin-I Converting Enzyme, Renin, and Angiotensin Converting Enzyme 2

in Translational Pharmacology

Carlos P. Vio
Pedro Gallardo
Carlos Cespedes
Daniela Salas
Jessica Diaz-Elizondo
Natalia Mendez

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00920

4,743 views
5 citations

Original Research

Published on 17 Jun 2020

Metabolomic Analysis of the Effects of Adipose-Derived Mesenchymal Stem Cell Treatment on Rats With Sepsis-Induced Acute Lung Injury

in Translational Pharmacology

Yuqing Cui
Shaohua Liu
Xiaojuan Zhang
Xianfei Ding
Xiaoguang Duan
Zijia Zhu
Ji Zhang
Huoyan Liang
Dong Wang
Guojun Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00902

4,738 views
20 citations

Original Research

Published on 17 Jun 2020

Novel Histone Deacetylase Inhibitors and HIV-1 Latency-Reversing Agents Identified by Large-Scale Virtual Screening

in Translational Pharmacology

Donya Naz Divsalar
Conrad Veranso Simoben
Cole Schonhofer
Khumoekae Richard
Wolfgang Sippl
Fidele Ntie-Kang
Ian Tietjen

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00905

5,277 views
17 citations

Mini Review

Published on 17 Jun 2020

Metformin during Pregnancy: Effects on Offspring Development and Metabolic Function

in Translational Pharmacology

Gonzalo Jorquera
Bárbara Echiburú
Nicolás Crisosto
Ramón Sotomayor-Zárate
Manuel Maliqueo
Gonzalo Cruz

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00653

74,217 views
19 citations

Case Report

Published on 12 Jun 2020

Intensive Hemodiafiltration Successfully Removes Ganciclovir Overdose and Largely Exceeds Reported Elimination During Hemodialysis—A Case Report and Review of the Literature

in Translational Pharmacology

Verena Gotta
Anne Leuppi-Taegtmeyer
Mirjam Gessler
Marc Pfister
Daniel Müller
Andreas Werner Jehle

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00882

3,115 views
2 citations

Navigation group

Articles

Redox Imbalance and Oxidative DNA Damage During Isoniazid Treatment of HIV-Associated Tuberculosis: A Clinical and Translational Pharmacokinetic Study

Rationale for Considering Oral Idasanutlin as a Therapeutic Option for COVID-19 Patients

From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery

Improving the Therapeutic Effect of Ultrasound Combined With Microbubbles on Muscular Tumor Xenografts With Appropriate Acoustic Pressure

Advance in Drug Delivery for Ageing Skeletal Muscle

Application of Pharmacokinetic-Pharmacodynamic Modeling in Drug Delivery: Development and Challenges

Pharmacogenetic Testing for Prevention of Severe Cutaneous Adverse Drug Reactions

Accelerating Therapeutics for Opportunities in Medicine: A Paradigm Shift in Drug Discovery

Drug Repositioning for Noonan and LEOPARD Syndromes by Integrating Transcriptomics With a Structure-Based Approach

Editorial: Bubbles, Droplets and Micelles for Acoustically-Mediated Drug/Gene Delivery

Inhibition of Plasminogen Activator Inhibitor-1 Activation Suppresses High Fat Diet-Induced Weight Gain via Alleviation of Hypothalamic Leptin Resistance

Dietary Potassium Downregulates Angiotensin-I Converting Enzyme, Renin, and Angiotensin Converting Enzyme 2

Metabolomic Analysis of the Effects of Adipose-Derived Mesenchymal Stem Cell Treatment on Rats With Sepsis-Induced Acute Lung Injury

Novel Histone Deacetylase Inhibitors and HIV-1 Latency-Reversing Agents Identified by Large-Scale Virtual Screening

Metformin during Pregnancy: Effects on Offspring Development and Metabolic Function

Intensive Hemodiafiltration Successfully Removes Ganciclovir Overdose and Largely Exceeds Reported Elimination During Hemodialysis—A Case Report and Review of the Literature